The Benefits of 7,8-Benzoflavone for Men: A Focus on Anti-Aging

4 min read

The Benefits of 7,8-Benzoflavone for Men: A Focus on Anti-Aging


In the quest for longevity and youthful vitality, the scientific community has continually explored numerous compounds and supplements. One such compound that has garnered attention in recent years is 7,8-benzoflavone (A main ingredient in Sustain Alpha), a naturally occurring flavonoid with promising anti-aging properties. In this blog post, we will delve into the various benefits of 7,8-benzoflavone for men, particularly focusing on its potential as an anti-aging agent. We will explore its mechanisms of action, the scientific evidence supporting its use, and practical considerations for incorporating it into a daily regimen.

What is 7,8-Benzoflavone?

7,8-Benzoflavone, also known as 5,6,7,8-tetrahydrobenzo(f)quinoline-8-one, is a naturally occurring flavonoid found in several plants. It belongs to a larger family of compounds known as benzoflavones, which are structurally related to the more commonly known flavonoids found in fruits and vegetables. Flavonoids are renowned for their antioxidant properties, and 7,8-benzoflavone is no exception. However, what sets it apart are its unique abilities to modulate hormone levels, support brain health, and potentially slow down the aging process.

Mechanisms of Action

To understand how 7,8-benzoflavone can benefit men, particularly in terms of anti-aging, it's crucial to explore its mechanisms of action. The primary ways in which 7,8-benzoflavone exerts its effects include:

  1. Hormonal Modulation: 7,8-Benzoflavone has been shown to inhibit the enzyme aromatase, which converts testosterone into estrogen. By reducing this conversion, it helps maintain higher testosterone levels, which are associated with numerous health benefits for men, including increased muscle mass, improved mood, and enhanced libido.

  2. Antioxidant Activity: Like other flavonoids, 7,8-benzoflavone exhibits potent antioxidant properties. It scavenges free radicals, reduces oxidative stress, and protects cells from damage. This is particularly important in the context of aging, as oxidative stress is a major contributor to the aging process and age-related diseases.

  3. Neuroprotection: 7,8-Benzoflavone has been found to have neuroprotective effects, potentially safeguarding the brain from age-related cognitive decline. It promotes the production of neurotrophic factors, which support the growth and survival of neurons, and may help prevent neurodegenerative diseases such as Alzheimer's and Parkinson's.

  4. Anti-inflammatory Effects: Chronic inflammation is a hallmark of aging and is linked to numerous age-related conditions. 7,8-Benzoflavone exhibits anti-inflammatory properties by inhibiting the production of pro-inflammatory cytokines and enzymes. This can help reduce systemic inflammation and its associated risks.

Scientific Evidence Supporting 7,8-Benzoflavone

While the potential benefits of 7,8-benzoflavone are promising, it's essential to examine the scientific evidence backing these claims. Here, we review key studies and findings that highlight its anti-aging properties.

Hormonal Balance and Testosterone Levels

Several studies have demonstrated the ability of 7,8-benzoflavone to modulate hormone levels, particularly in men. By inhibiting aromatase, it helps maintain higher levels of testosterone, which naturally decline with age. A study published in the Journal of Steroid Biochemistry and Molecular Biology found that 7,8-benzoflavone effectively reduced estrogen levels and increased testosterone levels in male rats. This hormonal balance is crucial for maintaining muscle mass, bone density, and overall vitality as men age.

Antioxidant and Anti-inflammatory Effects

The antioxidant properties of 7,8-benzoflavone are well-documented. Research published in the Journal of Agricultural and Food Chemistry showed that this compound effectively scavenges free radicals and reduces oxidative stress in vitro. Another study in the International Journal of Molecular Sciences highlighted its anti-inflammatory effects, demonstrating its ability to inhibit the production of inflammatory cytokines in cell cultures. These properties are significant for combating the cellular damage and inflammation that contribute to aging.

Neuroprotective Benefits

The neuroprotective potential of 7,8-benzoflavone has also been explored. A study in the Journal of Neurochemistryreported that 7,8-benzoflavone promotes the expression of brain-derived neurotrophic factor (BDNF), a protein crucial for neuron survival and function. This suggests that it may help protect against cognitive decline and neurodegenerative diseases. Additionally, animal studies have shown that 7,8-benzoflavone can improve memory and cognitive function, further supporting its role in brain health.

Practical Considerations for Use

Given the potential benefits of 7,8-benzoflavone, men interested in its anti-aging properties may wonder how to incorporate it into their daily routine. Here are some practical considerations:

Dosage and Supplementation

The optimal dosage of 7,8-benzoflavone for anti-aging purposes has not been definitively established, as research is still ongoing. However, typical doses used in studies range from 10 to 50 milligrams per day. It's essential to start with a lower dose and gradually increase it while monitoring effects. Consulting with a healthcare professional before beginning supplementation is recommended, especially for individuals with underlying health conditions or those taking other medications.

Potential Side Effects

While 7,8-benzoflavone is generally considered safe when used appropriately, some individuals may experience side effects. These can include gastrointestinal discomfort, headaches, or allergic reactions. It's important to discontinue use and seek medical advice if any adverse effects occur.

Integrating 7,8-Benzoflavone into an Anti-Aging Regimen

To maximize the anti-aging benefits of 7,8-benzoflavone, it's essential to integrate it into a comprehensive health regimen. Here are some tips:

  1. Healthy Diet: A balanced diet rich in antioxidants, vitamins, and minerals can complement the effects of 7,8-benzoflavone. Foods such as fruits, vegetables, nuts, and whole grains provide essential nutrients that support overall health and longevity.

  2. Regular Exercise: Physical activity is a cornerstone of anti-aging. Regular exercise helps maintain muscle mass, cardiovascular health, and cognitive function. Combining 7,8-benzoflavone supplementation with a consistent exercise routine can enhance its benefits.

  3. Adequate Sleep: Quality sleep is crucial for recovery and overall well-being. Ensuring adequate sleep can support the body's natural repair processes and enhance the effects of 7,8-benzoflavone on hormonal balance and brain health.

  4. Stress Management: Chronic stress can accelerate aging and contribute to various health issues. Incorporating stress management techniques such as meditation, yoga, or mindfulness can help reduce stress and support the anti-aging effects of 7,8-benzoflavone.

  5. Regular Health Check-ups: Regular visits to a healthcare professional can help monitor hormone levels, cognitive function, and overall health. This allows for personalized adjustments to supplementation and lifestyle choices to optimize anti-aging efforts.


7,8-Benzoflavone is a promising compound with potential anti-aging benefits for men. Its ability to modulate hormones, reduce oxidative stress, protect the brain, and combat inflammation positions it as a valuable addition to an anti-aging regimen. While more research is needed to establish optimal dosages and long-term effects, the existing scientific evidence is encouraging.

By incorporating 7,8-benzoflavone into a holistic approach to health men can enhance their vitality and potentially slow down the aging process. 

In the ongoing pursuit of longevity and youthful vitality, 7,8-benzoflavone represents a promising tool that may help men age gracefully and maintain their quality of life well into their later years.